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Covalent methods for immobilization of thiolated b

来源:乌哈旅游
专利内容由知识产权出版社提供

专利名称:Covalent methods for immobilization of

thiolated biomolecules on siliceous andmetallic surfaces

发明人:Rastislav Levicky,Patrick A. Johnson,Adrian

Horgan

申请号:US11316566申请日:20051222

公开号:US20070072199A1公开日:20070329

摘要:The present invention is directed to methods for immobilizing molecules onsiliceous and metallic surfaces. Molecules are immobilized on siliceous or metallicsurfaces by stable covalent linkages that are capable of withstanding prolonged use andelevated temperatures. Further, the methods of the present invention describe less-complicated chemistries for the immobilization of molecules that will benefit thereproducibility, efficiency and effectiveness of applications in sensing, chromatography,medical diagnostics and related areas where specific recognition between immobilizedand free molecules provides diagnostic information or serves as part of a purification orseparations process.

申请人:Rastislav Levicky,Patrick A. Johnson,Adrian Horgan

地址:Irvington NY US,New York NY US,Essex GB

国籍:US,US,GB

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