Preparation of 3-aminomethyl-3,5,5-trimethylcycloh

专利名称：Preparation of 3-aminomethyl-3,5,5-trimethylcyclohexylamine

发明人：Guido Voit,Tom Witzel,Boris

Breitscheidel,Wolfgang Harder,HermannLuyken,Axel Paul,Karl-Heinz Ross,Peter Wahl

申请号：US08/608485申请日：19960228公开号：US05756845A公开日：19980526

摘要：A process for the preparation of 3-aminomethyl-3,5,5-trimethylcyclohexylamine from 3-cyano-3,5,5-trimethylcyclohexanone which requiresthree spatially separated reaction spaces, in order to carry out the following three stepsin sequence:

a) reacting the 3- cyano- 3,5,5-trimethylcyclohexanone with excess ammonia on acidicmetal- oxide catalysts in a first reaction space at from 20° to 150. degree. C. and from 50to 300 bar,

b) hydrogenating the resultant reaction products using hydrogen in a second reactionspace in the presence of excess ammonia and preferably liquid ammonia onhydrogenation catalysts, optionally using basic components or on neutral or basicsupports at from 50° to 100° C. and at from 50 to 300 bar, and

c) hydrogenating the resultant reaction products in the presence of hydrogen andalso ammonia in a third reaction space on hydrogenation catalysts, optionally using basic

components or on neutral or basic supports at from 110° to 160° C. and at from 150 to300 bar.

These three steps in sequence provide a substantially complete reaction of theoriginal 3-cyano-3,3,5- trimethylcyclohexanone reactant with a yield of 96% of the desireddiamino product in which the cis- content of the diamine is 70%.

申请人：BASF AKTIENGESELLSCHAFT

代理人：John H. Shurtleff

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