专利名称:METHOD AND APPARATUS FOR
SUSTAINING VIABILITY OF BIOLOGICALCELLS ON A SUBSTRATE
发明人:Timothy E. McKnight,Anatoli V.
Melechko,Michael L. Simpson
申请号:US11624040申请日:20070117
公开号:US20080171386A1公开日:20080717
专利附图:
摘要:A method for the transient transformation of a living biological cell having an
intact cell membrane defining an intracellular domain, and an apparatus for the transienttransformation of biological cells. The method and apparatus include introducing acompartmentalized extracellular component fixedly attached to a cellular penetrantstructure to the intracellular domain of the cell, wherein the cell is fixed in a
predetermined location and wherein the component is expressed within in the cell whilebeing retained within the compartment and wherein the compartment restricts themobility and interactions of the component within the cell and prevents transference ofthe component to the cell.
申请人:Timothy E. McKnight,Anatoli V. Melechko,Michael L. Simpson
地址:Greenback TN US,Oak Ridge TN US,Knoxville TN US
国籍:US,US,US
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