专利名称:Chemilumuniscent acridine derivatives and
their use in luminescence immunoassays
发明人:MOLZ, PETER, DR.,SKRZIPCZYK, HEINZ-JURGEN, DR.,LUBBERS, HENNING,DR.,STRECKER, HELMUT, DR.,SCHNORR,GERD, DR.,KINKEL, TONIO, DR.
申请号:EP87112022.6申请日:19870819公开号:EP0257541A2公开日:19880302
专利附图:
摘要:A chemiluminescent acridinium derivative of the formula I in which R<1> ishydrogen, an alkyl, alkenyl or alkynyl radical having 1 to 10 carbon atoms, a benzyl oraryl group, R<2> and R<3> are hydrogen, an alkyl group having 1 to 4 carbon atoms, asubstituted or unsubstituted amino group, a carboxyl, C1-C4-alkoxy, cyano or nitro groupor halogen, R<4> represents a radical in which a sulphonamide group is bonded directlyto the carbonyl group via the nitrogen or represents a thioalkyl or thioaryl radical of theformula II - S - X - R<5> (II) where X is a branched or unbranched aliphatic or aromaticgroup, which can also contain hetero atoms and R<5> is a reactive group which undermild conditions can selectively form a bond with amino, carboxyl, thiol or other functionalgroups in substances of biological interest, and A<(-)> is an anion impairingchemiluminescence; and its use in luminescence immunoassays.
申请人:HOECHST AKTIENGESELLSCHAFT
地址:65926 Frankfurt am Main DE
国籍:DE
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